Wellbutrin and Alcohol: Side Effects, Interaction, Withdrawal, Safety

wellbutrin and alcohol

This may result in people experiencing worse and more dangerous side effects from these medications. This drug may make you dizzy or affect your coordination. Alcohol or marijuana can make you more dizzy or affect your coordination. Do not drive, use machinery, or do anything that needs alertness until you can do it safely.

If you have an injury or medical condition that causes pain or spasms in your muscles, you might be given medications to relax them. Muscle relaxants are commonly used to treat back and neck pain, as well as certain kinds of headaches. You might not need to completely avoid alcohol if you are taking a blood thinner. The American Heart Association recommends limiting your intake to no more than one or two occasional drinks if you are on anticoagulant therapy.

Drinking may also affect your recovery from depression. Like other antidepressants, using bupropion with alcohol isn’t recommended, as it may increase your risk of experiencing certain side effects. Your healthcare provider may prescribe a modified dosage of Wellbutrin due to possible side effects or another health concern. Wellbutrin can be fairly fast-acting when used for weight loss.

The effects of the mix can be especially serious—if not deadly—when the cough medicine also contains alcohol. Some research has found that alcohol does not appear to worsen liver inflammation in certain people who take medication for their cholesterol. A 2006 Harvard study found that moderate alcohol use did not have a significant negative effect on the livers of men taking statins after heart surgery. If you take a blood thinner, even an occasional drink can increase your risk of internal bleeding. If you have angina, you might be prescribed a medication called nitroglycerin. Older adults are also more likely to experience problems, as the ability to clear both alcohol and drugs from the body is reduced with age.

You’ll find stories directly from other people about their mental health journeys, as well as the latest information about treatments. Wellbutrin SR is available as a generic drug called bupropion SR, and Wellbutrin XL is available as a generic called bupropion XL. A generic is a copy of the active drug in a brand-name medication. Your medical professional can help determine whether the generic form of Wellbutrin may be an option for you.

  • The truth is the opposite, with moderation, you shouldn’t expect anything bad to happen to you.
  • The stress and sadness of moving can sometimes lead to relocation depression.
  • Drinking can counteract the benefits of your antidepressant medication, making your symptoms more difficult to treat.
  • Here are some common antibiotic and antifungal medications that can potentially have worse side effects when mixed with alcohol.

As a result, the U.S. boxed warning for bupropion for smoking cessation changed. However, the report notes that these reactions remain concerning, especially in patients with severe mood disorders or schizophrenia. This FDA report was explicitly related to the use of bupropion in smoking cessation.

Bupropion (Wellbutrin)

As with other drugs, Wellbutrin may cause side effects that can be mild or serious. For more information, we encourage you to keep reading. For me, I’m always really depressed the day after drinking, so it kinda nullifies the positive effect for me. I couldn’t stomach alcohol very much while on it, and made me piss like a horse drinking beer. I used to be able to sink a case yet now can hardly handle an 8 pack.

So, you may gain or lose weight while you’re taking Wellbutrin because your depression symptoms are getting better. Wellbutrin itself may not necessarily cause any weight changes. If you find that the side effects of Wellbutrin bother you, we recommend talking with your medical professional or pharmacist. For more complete choices sober living information about possible side effects of Wellbutrin, you can talk with your medical professional or pharmacist. They may also be able to recommend ways to help prevent and ease side effects. It’s important to note that some antidepressants — like monoamine oxidase inhibitors — have more dangerous interactions than SSRIs.

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If you are taking Wellbutrin, it is recommended to avoid alcohol consumption, if possible, or at least minimize use. Mixing alcohol and medicines puts you at risk for dangerous reactions. Protect yourself by eco sober house cost avoiding alcohol if you are taking a medication and don’t know its effect. To learn more about a medicine and whether it will interact with alcohol, talk to your pharmacist or other health care provider.

Medically Supervised Detox Programs for Alcohol Use

It’s also prescribed to help people stop smoking under the brand name Zyban. The effectiveness of oral contraceptives isn’t affected by alcohol, so it’s OK to enjoy a drink here and there when taking the pill. Pharmacokinetic interactions between cyclosporine and bupropion or methylphenidate. However, eating a healthy diet and being physically active have much greater health benefits and have been more extensively studied. Exposure to antidepressants during pregnancy and risk of ADHD in the offspring. Think about asking a loved one or friend to come with you to your appointment.

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Learn more about what the research says and everything you need to know to try it for yourself. If you still have questions about Wellbutrin and its possible interactions, talk with your doctor. There have been reports of people taking Wellbutrin who had a false-positive result on urine tests checking for amphetamines. For this reason, it’s still important to check with your doctor or pharmacist before taking any of these products while taking Wellbutrin.


People may develop AUD because the “high” feeling from alcohol may temporarily relieve anxiety. However, it can also make people dependent on alcohol as a form of self-medication to feel better. This section looks at some of the risks of mixing alcohol and Wellbutrin. Depression is a mood disorder that can affect a person’s daily life. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations.

wellbutrin and alcohol

In short-term studies, antidepressants increased the risk of suicidality in children, adolescents and young adults when compared to placebo. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24. Adults ages 65 and older taking antidepressants have a decreased risk of suicidality. Patients, their families and caregivers should be alert to the emergence of anxiety, restlessness, irritability, aggressiveness and insomnia. If these symptoms emerge, they should be reported to the patient’s prescriber or healthcare professional.

In addition, Wellbutrin may interact with certain antidepressants in a way that increases the risk of side effects from the other antidepressant. Verywell Health’s content is for informational and educational purposes only. There are several products with the active ingredient bupropion. Do not take more than one product that contains bupropion since this may increase your risk of having a seizure.

When to avoid Wellbutrin

This can help lessen your risk of side effects after stopping the drug. Aside from worsening depression, drinking alcohol while taking Cymbalta raises the risk of liver damage. Both alcohol and Cymbalta can cause liver injury on their own. However, the risk goes up when they are taken together — especially if you have multiple drinks at a time.

wellbutrin and alcohol

Depressed mood and lack of interest in activities may need up to 6-8 weeks to fully improve. Bupropion should not be taken with or within two weeks of taking monoamine oxidase inhibitors . These include phenelzine (Nardil®), tranycypromine (Parnate®), isocarboxazid (Marplan®), and selegiline (Emsam®). Bupropion IR is usually taken 2 or 3 times per day with 4-6 hours between doses. The dose usually ranges from 100 mg twice daily to 150 mg three times daily, with the last dose taken mid-afternoon. SAD is a type of depression that occurs mainly during the autumn-winter season.

Mixing Wellbutrin (Bupropion) And Alcohol — Interactions And Side Effects

They can use this information to adjust your treatment plan as needed. Wellbutrin has a boxed warning about suicidal thoughts and behaviors. A boxed warning appears on the drug’s label and alerts you to possible serious https://rehabliving.net/ risks. This was a common side effect in studies of Wellbutrin SR and Wellbutrin XL. For example, after taking Wellbutrin you may have symptoms of anxiety, such as feeling restless or having trouble falling asleep.

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